Opening image: Ribbon model of human myoglobin. Myoglobin contains eight α helices, designated by the letters A through H, counting from the N-terminus. These helices provide a rigid structural framework for the heme pocket. the protein as wireframe.
The heme group is shown in CPK colors. spacefilled model.
In this tutorial you will learn how myoglobin binds oxygen. However, the mechanism of oxygen binding is identical in all myoglobins and hemoglobins. After a brief description of the tertiary structure of myoglobin, we will look at how the protein provides a pocket into which the O2 can fit. Finally, we will discuss what happens when the heme group binds oxygen.