From Colorado State University

37. Ta, A.N.; McNaughton, B.R. “Antibody and Antibody Mimetic Immunotherapeutics” submitted 2017.

36. Bruce, V.J.; McNaughton, B.R. “Evaluation of Nanobody Conjugates and Fusions as Bioanalytical Reagents” submitted 2017.

35. Zhou, Z.; Vaidyanathan, G.; McDougald, D.; Mo Kang, C.; Balyasnikova, I.; Devoogdt, N.; Ta, A.N.; McNaughton. B.R.; Zalutsky, M. "Single Domain Antibody 2Rs15d: 18F-labeling using a residualizing label and preliminary evaluation” submitted 2017.

34. Bruce, V.J.; Ta, A.N.; McNaughton, B.R. “Minimalist Antibodies and Mimetics: An Update and Recent ApplicationsChemBioChem 2016, 17, 1892.

33. Tennyson, R.L.; Walker, S.N.; Ikeda, T.; Harris, R.S.; Kennan, A.J.; McNaughton. B.R. “Helix-Grafted Pleckstrin Homology Domains Suppress HIV-1 Infection of CD4-Positive CellsChemBioChem 2016, 17, 1945.

32. Crawford, D.W.; Blakeley, B.D.; Chen, P.-H.; Sherpa, C.; Le Grice, S.F.J.; Laird-Offringa, I.A.; McNaughton, B.R. “An Evolved RNA Recognition Motif That Suppresses Tat/TAR-Dependent TranscriptionACS Chemical Biology 2016, 11, 2206.

31. Chapman, A.M.; McNaughton, B.R. “Scratching the Surface: Resurfacing Proteins to Endow New Properties and Function” Cell Chemical Biology 2016, 23, 543.

30. Bruce, V.J.; Lopez-Islas, M.; McNaughton, B.R. “Resurfaced Cell-Penetrating Nanobodies: A Potentially General Solution for Intracellularly Targeted Protein Drug DiscoveryProtein Science 2016, 25, 1129.

29. Gray, M.A.; Tao, R.N.; DePorter, S.M.; Spiegel, D.A.; McNaughton, B.R. “A Nanobody Activation Immunotherapeutic That Selectively Destroys HER2-Positive Breast Cancer CellsChemBioChem 2016, 17, 155. This paper was highlighted on the cover.

28. Chapman, A.M.; McNaughton, B.R. “Synthetic Proteins Potently and Selectively Bind the Oncoprotein Gankyrin, Modulate Its Interaction with S6 ATPase, and Suppress Gankyrin/MDM2-Dependent Uniquitination of p53ACS Chemical Biology 2015, 10, 1880.

27. Walker, S.N.; Tennyson, R.L.; Chapman, A.M.; Kennan, A.J.; McNaughton, B.R. “GLUE That Sticks to HIV: A Helix-Grafted GLUE Protein That Selectively Binds HIV gp41 N-terminal Helical RegionChemBioChem 2015, 16, 219.

26. Chapman, A.M.; Rogers, B.E.; McNaughton, B.R. “Characterization of the Binding Interaction Between the Oncoprotein Gankyrin and a Grafted S6 ATPaseBiochemistry 2014, 53, 6857.

25. Chapman, A.M.; McNaughton, B.R. “Resurfaced Shape-Complementary Proteins That Selectively Bind the Oncoprotein Gankyrin ACS Chemical Biology 2014, 9, 2223.

24. DePorter, S.M.; McNaughton, B.R. “Engineered M13 Bacteriophage Nanocarriers for Intracellular Delivery of Exogenous Proteins to Human Prostate Cancer Cells” Bioconjugate Chemistry 2014, 25, 1620. This work was listed as a ‘most read’ paper

23. Mohan, U.; Burai, R.; McNaughton, B.R. “Reactivity Between Acetone and Single-Stranded DNA Containing a 5’-Terminated 2’-Fluoro-N7-Methyl Guanine” Tetrahedron Letters 2014, 55, 3358.

22. Blakeley, B.D.; McNaughton, B.R. “Synthetic RNA Recognition Motif Proteins that Selectively Recognize HIV-1 Trans-Activation Response Element Hairpin RNAACS Chemical Biology 2014, 9, 1320.

21. DePorter, S.M; Lui, I.; Bruce, V.J.; Gray, M.A.; Lopez-Islas, M.; McNaughton, B.R. "Mutagenesis Modulates the Uptake Efficiency, Cell-Selectivity, and Functional Enzyme Delivery of a Protein Transduction Domain" Molecular BioSystems 201410, 18This work was listed as a 'most read' paper.

20. Blakeley, B.D.; Shattuck, J.; Coates, M.B.; Tran, E.; Laird-Offringa, I.A.; McNaughton, B.R. "Analysis of Protein - RNA Complexes Involving an RNA Recognition Motif Engineered to Bind RNA Hairpins with 7- and 8-Nucleotide Loops" Biochemistry 2013, 52, 4745. This work was listed as a 'most read' paper.

19. Mohan, U.; Burai, R.; McNaughton, B.R. "In Vitro Evolution of a Friedel-Crafts Deoxyribozyme" Organic & Biomolecular Chemistry 2013, 11, 2241.

18. DePorter, S.M.; Lui, I.; Mohan, U.; McNaughton, B.R. "A Protein Transduction Domain with Cell Uptake and Selectivity Profiles that Are Controlled by Multivalency Effects" Chemistry & Biology 2013, 20, 434.  This work was featured in SciBX (volume 6, number 18, 2013)

17. DePorter, S.M.; Hendricks, N.K.; Gray, M.A.; McNaughton, B.R. "A One-Pot Synthesis of Micron-Sized and Nanoscale Poly(N-acryloxysuccinimide-co-N-vinylpyrrolidone) Particles" Tetrahedron Letters 2012, 53, 6436. This work is highlighted on the cover of this issue.

16. DePorter, S.M.; Lui, I; McNaughton, B.R. "Programmed Cell Adhesion and Growth on Cell-Imprinted Polyacrylamide Hydrogels" Soft Matter 2012, 8, 10403. 

15. Blakeley, B.D.; DePorter, S.M.; Mohan, U.; Burai, R.; Tolbert, B.S.; McNaughton, B.R. "Methods for Identifying and Characterizing Interactions Involving RNA" Tetrahedron 2012, 68, 8837. 

14. Blakeley, B.D.; Chapman, A.M.; McNaughton, B.R. "Split-Superpositive GFP Reassembly is a Fast, Efficient, and Robust Method for Detecting Protein-Protein Interactions In Vivo" Molecular BioSystems 2012, 8, 2036. (plasmids encoding split-superpositive GFP fragments can be purchased through Addgene) This work was listed as a 'most read' paper.

13. Burai, R.; Chatwichien, J.; McNaughton, B.R. "A Programmable Build - Couple Approach to the Synthesis of Heterofunctionalized Polyvalent Molecules" Organic & Biomolecular Chemistry 2011, 9, 5056.

From Harvard & University of Rochester

12. Cronican, J.J.; Thompson, D.B.; Beier, K.T.; McNaughton, B.R.; Cepko, C.L.; Liu, D.R. "Potent Delivery of Functional Proteins into Mammalian Cells in Vitro and in Vivo Using a Supercharged Protein" ACS Chemical Biology 2010, 5, 747.

11. McNaughton, B.R.; Gareiss, P.C.; Jacobs, S.E.; Fricke, A.F.; Scott, G.A.; Miller, B.L. "A Potent Activator of Melanogenesis Identified from Small Molecule Screening” ChemMedChem 2009, 4, 1583.

10. McNaughton, B.R.; Cronican, J.J.; Thompson, D.B.; Liu, D.R. "Mammalian Cell Penetration, siRNA Transfection, and DNA Transfection by Supercharged Proteins" Proc. Natl. Acad. Sci., U.S.A. 2009, 106, 6111. This work is featured as a Research Highlight in Nature Methods. 

9. Gareiss, P.C.; Sobczak, K.; McNaughton, B.R.; Palde, P.B.; Thornton, C.A.; Palde, P.; Miller, B.L. “Dynamic Combinatorial Selection of Small Molecules Capable of Inhibiting the (CUG) Repeat RNA – MBNL1 Interaction in Vitro: Discovery of Lead Compounds Targeting Myotonic Dystrophy (DM1)J. Am. Chem. Soc. 2008, 130, 16254.

8. McNaughton, B.R.; Miller, B.L. “A Facile Synthesis of 2-Ethyl-Quinoline-3-Carboxylic Acid HydrochlorideOrg. Synth. 2008, 85, 27

7. Rozenman, M.M.; McNaughton, B.R.; Liu, D.R. “Solving Chemical Problems Through the Application of Evolutionary PrinciplesCurr. Opinion Chem. Biol. 2007, 11, 259.

6. McNaughton, B.R.; Gareiss, P.C.; Miller, B.L. “Identification of a High-Affinity and Selective Ligand for the HIV-1 Frameshift-Inducing RNA Stemloop from an 11,325 Member Resin Bound Dynamic Combinatorial Library J. Am. Chem. Soc. 2007, 129, 11306.

5. Palde, P.; McNaughton, B.R.; Ross, N.T.; Gareiss, P.C.; Mace, C.R.; Spitale, R.C.; Miller, B.L. “Single-Step Synthesis of Functional Organic Receptors via a Tridirectional Minisci ReactionSynthesis 2007, 15, 2287.

4. McNaughton, B.R.; Miller, B.L. “Resin-Bound Dynamic Combinatorial ChemistryOrg. Lett. 2006, 8, 1803.

3. McNaughton, B.R.; Bucholtz, K.M.; Moure, A.C.; Miller, B.L. “Self-Selection in Olefin Cross Metathesis: A Study on the Effects of Remote FunctionalityOrg. Lett. 2005, 7, 733.

2. Ross, N.; McNaughton, B.R.; Miller, B.L. Drug Discovery Handbook. Wiley & Sons, (2004). Chapter 21 “Combinatorial Chemistry in the Drug Discovery Process” Buy on Amazon

1. McNaughton, B.R.; Miller, B.L. “A Mild and Efficient One-Step Synthesis of QuinolinesOrg. Lett. 2003, 5, 4257.

© McNaughton Lab, Colorado State University